Tam is having issues with her Ruger Mk.III 22/45. I shoot the Hunter version of the same pistol when I do metallic silhouette, which is a few times a month. The loaded chamber indicator and magazine safety are problems in this design, if you ask me. I haven’t had Tam’s specific problem, but I’ve had other weird malfs that resolve themselves when you remove and re-seat the mag. The magazine safety is just a bad bad idea, for a lot of reasons, and the loaded chamber indicator (also a bad idea) makes the chamber very difficult to clean. The LCI will get gunked up over time, which always makes me nervous, because the smooth operation of the spring on the Mk.III LCI is critical to prevent a strike on the LCI flag from setting off the round (such as if you drop the gun).
I chose to solve the problem of fussy internals by getting a Volquartsen trigger kit. It doesn’t get rid of the two bad features, but it’s much much better than the factory Ruger trigger, and I’ve yet to have any serious problems with stoppages and the like. It helps make the Mk.III into a pretty nice shooter. They also have a kit for the Mk.II as well. I would highly recommend.
I understand that Ruger wants the Mk.III line to be legal in as many states as possible, but my suggestion for Ruger would be to either go back to the original Mk.II design, or at the least make the LCI and mag safety easy to take out. In computer user interface design, it’s a given that you never want to cripple your advanced users for the sake of novices. That philosophy can be applied to pistols too, I think. You can’t really beat the price point of the Mk.III and Mk.II for what you get, and with the addition of the Volquartsen kit, can be just fine for competition use. It’s a shame that anti-gun politicians have turned this flagship brand in American shooting down such a wrong path.